- ￥880
- Bioss
- bs-12379P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12379P |
| 英文名称 | STC2 Antibody Blocking Peptide |
| 中文名称 | 斯钙素2封闭多肽 |
| 英文别名 | Stanniocalcin related protein; Stanniocalcin-2; Stanniocalcin-related protein; Stanniocalcin2; STC 2; STC related protein; STC-2; STC-related protein; STC2; STC2_HUMAN; STCRP. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Signaling Pathway > Calcium Signaling Stem Cells > Mesenchymal Stem Cells > Secreted Molecules |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes. |
| 相似性 | Belongs to the stanniocalcin family. |
| 功能 | Has an anti-hypocalcemic action on calcium and phosphate homeostasis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells). |
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STC2 Antibody Blocking Peptide(bs-12379P)-500ug
￥880
