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- Bioss
- bs-13655P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13655P |
| 英文名称 | MKLN1 Antibody Blocking Peptide |
| 中文名称 | MKLN1封闭多肽 |
| 英文别名 | MKLN 1; Mkln1; MKLN1_HUMAN; muskelin 1, intracellular mediator containing kelch motifs; Muskelin. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Adapters > Cytoplasmic |
| 亚细胞定位 | Cytoplasm. |
| 相似性 | Contains 1 CTLH domain. Contains 6 Kelch repeats. Contains 1 LisH domain. |
| 功能 | Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin 1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Muskelin is a 735 amino acid nuclear and cytoplasmic protein that mediates cytoskeletal responses and cell spreading to Thrombospondin 1, an extracellular matrix glycoprotein. Forming a CTLH complex with RMND5A, Ran BP-M and TWA1, Muskelin exists as two alternatively spliced isoforms. Muskelin is implicated as an isoform-specific anchoring protein for the prostaglandin EP3 receptor, and contains one LisH domain, a CTLH domain, six Kelch repeats and an N-terminal discoidin-like domain through which it self-associates via a head-to-tail mechanism. Human and mouse Muskelin share 98% amino acid seqeuence homology and are encoded by genes located on chromosomes 7q32.3 and 6 A3.3, respectively. |
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MKLN1 Antibody Blocking Peptide(bs-13655P)-500ug
￥880
