CEP85L Antibody Blocking Peptide(bs-15238P)-500ug

CEP85L Antibody Blocking Pepti

de(bs-15238P)-500ug
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  • ¥880
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  • bs-15238P
  • 2025年10月16日
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      500ug

    产品编号bs-15238P
    英文名称CEP85L Antibody Blocking Peptide
    中文名称6号染色体开放阅读框204封闭多肽
    英文别名bA57K17.2; C6orf204; centrosomal protein 85kDa-like; CE85L_HUMAN; Coiled-coil domain-containing protein C6orf204; NY-BR-15; RP11-57K17.2; Serologically defined breast cancer antigen NY-BR-15.
    纯化方法HPLC
    亚细胞定位Cytoplasm, cytoskeleton, centrosome (Probable). Note=Subcellular experiments using a GFP-tagged system produced a weak signal, rendering it difficult to confirm centrosome association.
    组织特异性soform 1 and isoform 4 are expressed in spleen, lymph, thymus, tonsil and peripheral blood leukocytes, with isoform 1 expressed at higher levels. Isoform 4 is detected in K-562 leukemia cells and in the blood of precursor T lymphoblastic lymphoma (T-ALL) patients.
    相似性Belongs to the CEP85 family.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf204 gene product has been provisionally designated C6orf204 pending further characterization.

     

     

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