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- 规格:
500ug
| 产品编号 | bs-23397P |
| 英文名称 | HO-1 Antibody Blocking Peptide |
| 中文名称 | 血红素氧合酶 1/热休克蛋白32封闭多肽 |
| 英文别名 | Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HO 1; HO; HO1; Hsp32; bK286B10; D8Wsu38e. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Cardiovascular > Atherosclerosis > Vascular Inflammation > Inflammatory mediators Cardiovascular > Blood > Platelets Cardiovascular > Vasculature > Endothelium Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > NFkB pathway Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Types of disease > Cancer Metabolism > Types of disease > Heart disease Metabolism > Types of disease > Neurodegenerative disease Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease Signal Transduction > Signaling Pathway > Nuclear Signaling > NFkB Pathway |
| 亚细胞定位 | Microsome. Endoplasmic reticulum. |
| 组织特异性 | Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). |
| 相似性 | Belongs to the heme oxygenase family. |
| 功能 | Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The hemeoxygenase-1 calls that the hemoglobin oxidizes to synthesize the enzyme again-1( hemeoxygenase-1, HO-1) is the catalyst enzyme that a kind of hemoglobin declines the solution, under the NADPH and the cell dye P-450 revivification enzymes and the member oxygen functions, the catalyst HO-1 hemoglobin declines the solution as the courage green vegetable, CO and irons, the former revivification has the very strong anti- to oxidize the ability after become the red vegetable of courage , the latter is a kind of important letter to make the member. |
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