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500ug
| 产品编号 | bs-11045P |
| 英文名称 | C1QL1 Antibody Blocking Peptide |
| 中文名称 | 补体组分1q子成分样蛋白1封闭多肽 |
| 英文别名 | C1q related factor; C1q-related factor; C1ql1; C1QRF; C1QRF_HUMAN; C1QTNF14; Complement component 1 Q subcomponent like 1; Complement component 1 Q subcomponent-like 1; CRF; Gliacolin. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Complement Neuroscience > Cell Adhesion Proteins > ECM Proteins |
| 亚基 | Interacts with BAI3 (By similarity). |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in brainstem. |
| 相似性 | Contains 1 C1q domain. Contains 1 collagen-like domain. |
| 功能 | May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C1q is part of the C1 enzyme complex, which activates the serum complement system. The residues of the globular domain in C1q share homology with several other secreted and membrane-bound collagen or collagen-like proteins, including pre-cerebellin and collagen types VIII and X, as well as the human and mouse genes encoding Apm1/BPB80 and AdipoQ/ACRP30, respectively. These various C1q-related proteins are found in adipose serum, corneal endothelium, chondrocytes and cerebral Purkinje cells. C1qL1 (complement component 1, q subcomponent-like 1), also known as CRF or C1QRF, is a polypeptide with a hydrophobic signal sequence, a collagenous region and a globular domain at the carboxy terminus, which shares homology to the C1q globular domain. C1qL1 transcripts are most abundant in areas of the nervous system that are associated with motor function, including cerebral Purkinje cells, the pons, the accessory olivary nucleus, and the red nucleus. The similarity of mouse C1qL1 to human C1qL1 suggests a conserved and important role for the protein. In humans, the gene encoding C1qL1 maps to chromosome 17q21. |
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C1QL1 Antibody Blocking Peptide(bs-11045P)-500ug
¥880







