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- Bioss
- bs-11039P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11039P |
| 英文名称 | STXBP6 Antibody Blocking Peptide |
| 中文名称 | 突触融合结合蛋白6封闭多肽 |
| 英文别名 | Amisyn; HSPC156; STXB6_HUMAN; STXBP6; Syntaxin binding protein 6; Syntaxin-binding protein 6. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > ECM Proteins Neuroscience > Neurotransmission > Secretory Vesicles Neuroscience > Neurotransmission > Secretory Vesicles > SNAPs & SNAREs |
| 亚基 | Part of a ternary complex containing SNAP25 and STX1A that can be dissociated by NAPA and NSF. Interacts with STX4A. |
| 亚细胞定位 | Cytoplasm. Membrane. |
| 组织特异性 | Detected at low levels in brain, and at very low levels in heart, adrenal gland, testis, liver and kidney. |
| 相似性 | Contains 1 v-SNARE coiled-coil homology domain. |
| 功能 | Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding. |
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STXBP6 Antibody Blocking Peptide(bs-11039P)-500ug
￥880
