- ￥880
- Bioss
- bs-0608P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-0608P |
| 英文名称 | ICAM1 Antibody Blocking Peptide |
| 中文名称 | 细胞间粘附分子-1（CD54）封闭多肽 |
| 英文别名 | BB2; CD54 antigen;ICAM 1; ICAM-1; Cell surface glycoprotein P3.58; Human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B cells; ICAM1_HUMAN; MALA-2; MyD10; intercellular adhesion molecule 1 precursor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Angiogenesis > Endothelial Cell Markers Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Cell adhesion molecules Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Cell Type Markers > CD > Adhesion Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage |
| 亚基 | Homodimer (Probable). Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF. Binds to coxsackievirus A21 capsid proteins and acts as a receptor for this virus. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 翻译后修饰 | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
| 相似性 | Belongs to the immunoglobulin superfamily. ICAM family. ontains 5 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
ICAM1 Antibody Blocking Peptide(bs-0608P)-500ug
￥880
