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- Bioss
- bs-23357P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-23357P |
| 英文名称 | NMUR1 Antibody Blocking Peptide |
| 中文名称 | G蛋白偶联受体66/神经调节肽U受体1封闭多肽 |
| 英文别名 | FM-3; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; GPR66; Growth hormone secretagogue receptor family Member 3; Neuromedin U Receptor 1; Neuromedin-U receptor 1; NMU-R1; NMUR1; NMUR1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Types of disease > Cancer Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis Neuroscience > Neurology process > Metabolism Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for the neuromedin-U and neuromedin-S neuropeptides. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It’s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues. |
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NMUR1 Antibody Blocking Peptide(bs-23357P)-500ug
￥880
