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KCNK2 Antibody Blocking Peptid

e(bs-16902P)-500ug
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  • 2025年10月16日
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    产品编号bs-16902P
    英文名称KCNK2 Antibody Blocking Peptide
    中文名称钾离子通道蛋白2封闭多肽
    英文别名hTREK 1c; hTREK 1e; K2p2.1; K2P2.1 potassium channel; KCNK 2; Kcnk2; KCNK2_HUMAN; MGC126742; MGC126744; Outward rectifying potassium channel protein TREK 1; Outward rectifying potassium channel protein TREK-1; Outward rectifying potassium channel protein TREK1; Potassium channel subfamily K member 2; Potassium inwardly rectifying channel subfamily K member 2; Tandem pore domain potassium channel TREK 1; Tandem pore domain potassium channel TREK1; TPKC1; TREK 1; TREK 1 K(+) channel subunit; TREK; TREK-1 K(+) channel subunit; TREK1; TWIK related potassium channel 1; Two pore domain potassium channel TREK 1; Two pore domain potassium channel TREK-1; Two pore domain potassium channel TREK1; Two pore potassium channel 1; Two pore potassium channel TPKC1.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > Potassium Channels

    亚基Homodimer (Potential).
    亚细胞定位Membrane.
    组织特异性Isoform 4 is detected in kidney, adrenal gland and brain where it is preferentially expressed in the amygdala but not found in thalamus, hypothalamus, hippocampus or substantia nigra.
    翻译后修饰Phosphorylation at Ser-348 controls the reversible conversion from a leak channel to a voltage-dependent channel.
    相似性Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
    功能Outward rectifying potassium channel.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

     

     

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