- ￥880
- Bioss
- bs-17515P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17515P |
| 英文名称 | OSBP1 Antibody Blocking Peptide |
| 中文名称 | 氧固醇结合蛋白1封闭多肽 |
| 英文别名 | OSBP 1; OSBP; OSBP1_HUMAN; Oxysterol binding protein 1; Oxysterol-binding protein 1. |
| 纯化方法 | HPLC |
| 亚基 | Homodimer or homotrimer. Interacts with VAPA. |
| 亚细胞定位 | Cytoplasm. Golgi apparatus membrane. When bound to oxysterols, translocates to the periphery of Golgi membranes. |
| 组织特异性 | Widely expressed. |
| 相似性 | Belongs to the OSBP family. Contains 1 PH domain. |
| 功能 | Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008] |
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OSBP1 Antibody Blocking Peptide(bs-17515P)-500ug
￥880
