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INPP5K Antibody Blocking Pepti

de(bs-17506P)-500ug
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  • 2025年10月16日
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      500ug

    产品编号bs-17506P
    英文名称INPP5K Antibody Blocking Peptide
    中文名称SKIP蛋白封闭多肽
    英文别名43 kDa form skeletal muscle and kidney enriched inositol phosphatase; Inositol polyphosphate 5-phosphatase K; INP5K_HUMAN; INPP5K; muscle and kidney-enriched inositol phosphatase; PPS; skeletal muscle and kidney enriched inositol phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase.
    纯化方法HPLC
    亚细胞定位Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles.
    组织特异性Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.
    相似性Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.
    功能Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

     

     

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