- ￥880
- Bioss
- bs-17510P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-17510P |
| 英文名称 | SKIV2L2 Antibody Blocking Peptide |
| 中文名称 | ATP依赖的解旋酶SKIV2L2封闭多肽 |
| 英文别名 | 2610528A15Rik; ATP dependent helicase SKIV2L2; DOB1; SK2L2_HUMAN; KIAA0052; MGC142069; mKIAA0052; Mtr4; superkiller viralicidic activity 2 like 2 (S. cerevisiae); Superkiller viralicidic activity 2 like 2. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing Immunology > Immune System Diseases > Autoimmune |
| 亚基 | Component of a TRAMP-like complex, an ATP-dependent exosome regulatory complex consisting of an helicase (SKIV2L2/MTR4), an oligadenylate polymerase (PAPD5 or PAPD7), and a substrate specific RNA-binding factor (ZCCHC7 or ZCCHC8). Several TRAMP-like complexes exist with specific compositions and are associated with nuclear, or nucleolar RNA exosomes. Identified in the spliceosome C complex. |
| 亚细胞定位 | Nucleus, nucleoplasm. Nucleus, nucleolus. |
| 相似性 | Belongs to the helicase family. SKI2 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
| 功能 | May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SKIV2L2, or superkiller viralicidic activity 2 like 2, may be involved in pre-mRNA splicing. SKIV2L2 is an exosome-associated protein and may be involved in the recruitment of the exosome to pre-rRNA, to mediate the 3' end processing of 5.8S rRNA. |
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SKIV2L2 Antibody Blocking Peptide(bs-17510P)-500ug
￥880
