SYNGR3 Antibody Blocking Peptide(bs-11373P)-500ug

SYNGR3 Antibody Blocking Pepti

de(bs-11373P)-500ug
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  • bs-11373P
  • 2025年10月16日
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      500ug

    产品编号bs-11373P
    英文名称SYNGR3 Antibody Blocking Peptide
    中文名称神经细胞囊泡循环蛋白3封闭多肽
    英文别名SNG3_HUMAN; Synaptogyrin 3; Synaptogyrin-3; Synaptogyrin3; SYNGR 3; SYNGR3; SYNGR-3; MGC:20003; MGC20003; OTTHUMP00000158899.
    纯化方法HPLC
    亚基Interacts (via N-terminus) with SLC6A3 (via N-terminus) (By similarity).
    亚细胞定位Membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle (By similarity). Cell junction, synapse. Note=Found at the neuromuscular synapses (By similarity).
    组织特异性Expressed in brain and placenta.
    相似性Belongs to the synaptogyrin family.
    Contains 1 MARVEL domain.
    功能Involved in the positive regulation of dopamine transporter activity. Probably facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal (Synaptogyrins 1 and 3) and one ubiquitous (Synaptogyrin-2) isoform. Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as Cellugyrin has a tyrosine phosphorylated C-terminal cytoplasmic tail, and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. The SYNGR4 gene encodes for the 234 amino acid protein Synaptogyrin-4.

     

     

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