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- Bioss
- bs-13632P
- 2025年10月16日
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500ug
| 产品编号 | bs-13632P |
| 英文名称 | DLG5 Antibody Blocking Peptide |
| 中文名称 | 胎盘和前列腺相关蛋白DLG5封闭多肽 |
| 英文别名 | Discs large homolog 5 (Drosophila); Discs large homolog 5; Discs large protein LP DLG; Discs large protein P dlg; Discs large protein P-dlg; Disks large homolog 5; DLG 5; DLG5; DLG5_HUMAN; KIAA0583; Large type of P DLG; LP DLG; P DLG5; PDLG; Placenta and prostate DLG. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Adapters > Transmembrane |
| 亚细胞定位 | Cell junction. Cell membrane. Localized at sites of cell-cell contact. |
| 组织特异性 | Highly expressed in the placenta and prostate. Expressed at a lower level in the thyroid, spinal cord, trachea, adrenal gland, skeletal muscle, pancreas, heart, brain, liver and kidney. A short splice product shows more limited expression, being absent from at least the brain. |
| 相似性 | Belongs to the MAGUK family. Contains 1 CARD domain. Contains 1 guanylate kinase-like domain. Contains 4 PDZ (DHR) domains. Contains 1 SH3 domain. |
| 功能 | May play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in the transmission of extracellular signals to the membrane and cytoskeleton. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta. |
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DLG5 Antibody Blocking Peptide(bs-13632P)-500ug
￥880
