- ￥880
- Bioss
- bs-2330P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2330P |
| 英文名称 | RAP2B Antibody Blocking Peptide |
| 中文名称 | 原癌基因相关蛋白RAP2B封闭多肽 |
| 英文别名 | RAP 2B; RAP2B member of RAS oncogene family; Ras family small GTP binding protein RAP2B; Ras related protein RAP 2B; Ras related protein RAP2B ; Small GTP binding protein.RAP2B_HUMAN |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family |
| 亚基 | Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A |
| 亚细胞定位 | Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Associated with red blood cells-released vesicles |
| 组织特异性 | Expressed in red blood cells |
| 翻译后修饰 | Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK |
| 相似性 | Belongs to the small GTPase superfamily. Ras family. |
| 功能 | Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RAP2B belongs to a family of RAS-related GTP-binding proteins. RAP proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. However, at their 61st amino acid the glutamine in RAS proteins is replaced by threonine in RAP proteins. RAP2A interacts with phospholipase C, epsilon 1 (PLCE1). |
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RAP2B Antibody Blocking Peptide(bs-2330P)-500ug
￥880
