LARP7 Antibody Blocking Peptide(bs-17106P)-500ug

LARP7 Antibody Blocking Peptid

e(bs-17106P)-500ug
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  • bs-17106P
  • 2025年10月16日
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      500ug

    产品编号bs-17106P
    英文名称LARP7 Antibody Blocking Peptide
    中文名称LARP7蛋白封闭多肽
    英文别名DKFZp564K112; HDCMA18P; La related protein 7; La ribonucleoprotein domain family member 7; La ribonucleoprotein domain family member 7; La-related protein 7; LARP 7; larp7; LARP7_HUMAN; MGC104360; P TEFb interaction protein for 7SK stability; P-TEFb-interaction protein for 7SK stability; PIP7S.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    亚细胞定位Nucleus > nucleoplasm.
    翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    相似性Contains 1 HTH La-type RNA-binding domain.
    Contains 1 RRM (RNA recognition motif) domain.
    功能Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

     

     

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