HIVEP1 Antibody Blocking Peptide(bs-17459P)-500ug

HIVEP1 Antibody Blocking Pepti

de(bs-17459P)-500ug
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  • bs-17459P
  • 2025年10月16日
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      500ug

    产品编号bs-17459P
    英文名称HIVEP1 Antibody Blocking Peptide
    中文名称艾滋病病毒EP1封闭多肽
    英文别名Cirhin interaction protein; CIRIP; CRYBP1; GAAP; Gate keeper of apoptosis-activating protein; HIV EP1; HIV-EP1; HIVEP 1; Hivep1; Human immunodeficiency virus type I enhancer binding protein 1; Human immunodeficiency virus type I enhancer-binding protein 1; Major histocompatibility complex binding protein 1; Major histocompatibility complex-binding protein 1; MBP 1; MBP-1; Positive regulatory domain II binding factor 1; Positive regulatory domain II-binding factor 1; PRDII BF1; PRDII-BF1; Schnurri 1; ZAS1; ZEP1_HUMAN; Zinc finger protein 40; ZNF40; ZNF40A.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Immunology > Immune System Diseases > Antiviral Signaling > HIV-related

    Microbiology > Interspecies Interaction > Host Virus Interaction

    亚细胞定位Cytoplasm. Nucleus and Nucleus.
    相似性Contains 5 C2H2-type zinc fingers.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

     

     

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