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500ug
| 产品编号 | bs-17042P |
| 英文名称 | KIF18A Antibody Blocking Peptide |
| 中文名称 | 驱动蛋白家族成员18A封闭多肽 |
| 英文别名 | AU024633; B130001M12Rik; DKFZp434G2226; KI18A_HUMAN; KIF 18A; KIF18A; kinesin family member 18A; Kinesin like protein KIF18A; Kinesin-like protein KIF18A; Marrow stromal KIF18A; MGC27627; MS KIF18A; MS-KIF18A; RGD1561740; RP23 206C1.1. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin-like |
| 亚细胞定位 | Cell projection > ruffle. Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome. |
| 翻译后修饰 | Glycosylated. Ubiquitinated. |
| 相似性 | Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. |
| 功能 | Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KIF18A is a 898 amino acid protein that contains one kinesin-motor domain, which is responsible for the ATP-dependent movement of KIF18A across microtubules. KIF18A plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. Expression of KIF18A is induced by estrogen. |
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KIF18A Antibody Blocking Peptide(bs-17042P)-500ug
¥880







