- ￥880
- Bioss
- bs-14758P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14758P |
| 英文名称 | FAM171A2 Antibody Blocking Peptide |
| 中文名称 | FAM171A2蛋白封闭多肽 |
| 英文别名 | F1712_HUMAN; fam171a2; Family with sequence similarity 171, member A2; Protein FAM171A2. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Membrane. |
| 相似性 | Belongs to the FAM171 family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | FAM171A2 is a 826 single-pass type I membrane protein belonging to the FAM171 family and is encoded by a gene located on human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair and is specifically recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
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FAM171A2 Antibody Blocking Peptide(bs-14758P)-500ug
￥880
