- ￥880
- Bioss
- bs-7642P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7642P |
| 英文名称 | AGTRAP Antibody Blocking Peptide |
| 中文名称 | 血管紧张素Ⅱ受体相关蛋白封闭多肽 |
| 英文别名 | Angiotensin Ⅱ receptor associated protein; Angiotensin Ⅱ type I receptor associated protein; ATI receptor associated protein; ATRAP; MGC29646; Type 1 angiotensin Ⅱ receptor associated protein; ATRAP_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Blood > Blood Pressure regulation Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚基 | Interacts with GNB2L1/RACK1, and with the C-terminal region of AGTR1. |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles. |
| 组织特异性 | Ubiquitous but more abundant in kidney, heart, pancreas and thyroid. |
| 功能 | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | AGTRAP (Angiotensin II receptor-associated protein) interacts with the angiotensin II type 1 receptor and negatively regulates type 1 angiotensin II receptor-mediated signaling, by regulating receptor internalisation as well as mechanisms of receptor desensitization such as phosphorylation. |
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AGTRAP Antibody Blocking Peptide(bs-7642P)-500ug
￥880
