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- Bioss
- bs-12307P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12307P |
| 英文名称 | ENPEP Antibody Blocking Peptide |
| 中文名称 | 氨肽酶A封闭多肽 |
| 英文别名 | Aminopeptidase A; AMPE_HUMAN; AP-A; APA; CD249; CD 249; Differentiation antigen gp160; EAP; EC 3.4.11.7; BP1; Glutamyl aminopeptidase; Gp160; Ly51; Ly51/6C3 antigen. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Hypertrophy > Hormones Immunology > Adaptive Immunity > B Cells > CD Immunology > Adaptive Immunity > B Cells > Non-CD Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
| 相似性 | Belongs to the peptidase M1 family. |
| 功能 | Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Aminopeptidase A, also designated APA, gp160 human kidney differentiation antigen, glutamyl aminopeptidase, or enpep, is a differentiation-related kidney glycoprotein. As a cell surface, zinc-dependent metalloprotease, Aminopepti-dase A specifically cleaves amino-terminal acidic residues from peptide substrates such as Angiotensin II. APA is expressed on the surface of epithelial cells of the glomerulus and proximal tubule cells of the human nephron, where it may mediate the constitutive trafficking of Glut4-containing vesicles. These Glut4-containing vesicles are tissue-specific secretory-like microsomal structures that mediate insulin-dependent translocation of GLUT4 to the cell surface in fat and muscle cells. Mutations in the gp160/APA gene, including loss of protein expression or enzymatic activity, occur in 20% of primary clear cell renal carcinomas. |
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ENPEP Antibody Blocking Peptide(bs-12307P)-500ug
￥880
