TPGS1 Antibody Blocking Peptide(bs-17165P)-500ug

TPGS1 Antibody Blocking Peptid

e(bs-17165P)-500ug
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  • bs-17165P
  • 2025年10月16日
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      500ug

    产品编号bs-17165P
    英文名称TPGS1 Antibody Blocking Peptide
    中文名称电压门控离子通道蛋白TPGS1封闭多肽
    英文别名C19orf20; two pore segment channel 1; Gene trap ROSA b geo 22; GTRGEO22; PGs1; Tubulin polyglutamylase complex subunit 1.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > MT Associated Proteins > MAP

    亚基Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1.
    亚细胞定位Microtubule.
    功能TPGS1 may act in the targeting of the tubulin polyglutamylase complex. It is required for the development of the spermatid flagellum.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料TPCN1 is a widely expressed, 816 amino acid voltage-gated cation channel protein with predominant expression in lung, liver, heart and kidney. In the kidney, TPCN1 localizes to the inner medullary collecting ducts. In contrast with the distantly related four-domain voltage-gated calcium and sodium channels and the more closely related four-domain ion transport protein located on the surface of sperm cells (CatSper), TPCN1 is a two-domain channel. Similar to the four-domain channel structure, each of the two homologous domains that comprise TPCN1 contains six transmembrane segments (S1-S6) with a pore loop between S5 and S6 and a voltage sensor segment that is positively charged. TPCN1 has hydrophilic N- and C-termini that localize to the cytoplasm.

     

     

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