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- bs-48024P
- 2025年10月16日
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10ug/50ug/500ug
| 规格： | 10ug | 产品价格： | ￥1000.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥2000.0 |
| 规格： | 500ug | 产品价格： | ￥8000.0 |
| 产品编号 | bs-48024P |
| 英文名称 | Recombinant human G-CSF protein (Active, CHO) |
| 中文名称 | 重组人G-CSF (活性的, Tag free) |
| 英文别名 | rhG-CSF; GCSF; Colony stimulating factor 3 (granulocyte); CSF 3; CSF beta; CSF3; Csfg; Filgrastim; GCSA; Granulocyte colony stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin; Granulocyte Colony Stimulating Factors 3; CSF3_HUMAN ; |
| 中文别名 | 人G-CSF重组蛋白; 重组人G-CSF; 人重组G-CSF; 重组人G-CSF; 粒细胞集落刺激因子; 集落刺激因子; 粒细胞生长因子; 重组人粒细胞集落刺激因子; |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 实际分子量 | 21-25kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | 0.22μm-filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH7.4 |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors Immunology > Innate Immunity > Cytokines > CSFs |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells). |
| 相似性 | Belongs to the IL-6 superfamily. |
| 功能 | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins that regulate haematopoietic cell proliferation and differentiation. G-CSF was isolated initially as a factor supporting the growth of colonies of granulocytes in soft agar cultures. Cells of the monocyte/macrophage lineage are among the most prominent sources of G-CSF, but this factor can also be produced by normal cells of mesodermal origin, including vascular endothelial cells, fibroblasts, and mesothelial cells. Production of G-CSF can be induced in vitro in these cells by a wide variety of stimulatory agents, including LPS, TNF, IL-1, IL-3, I L-4, and IFN-Gamma. G-CSF is likely to play a role in the basal regulation of neutrophil production, and also functions as a primary regulatory factor controlling the neutrophil response to inflammatory stimuli. Furthermore, G-CSF exhibits other biological activities besides the proliferative effects, since G-CSF appears to modulate the distribution of neutrophils and progenitor cells within the body. |
The purity of the protein is greater than 95% as determined by reducing SDS-PAGE.
Measured in a cell proliferation assay using of murine NFS-60 cells is < 0.5 ng/ml, corresponding to a specific Bioactivity of ≥ 1 x 10^7 units/mg.
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Recombinant human G-CSF protein (Active, CHO)(bs-48024P)-10ug/50ug/500ug
￥1000 - 8000
