RTF1 Antibody Blocking Peptide(bs-12261P)-500ug

RTF1 Antibody Blocking Peptide

(bs-12261P)-500ug
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  • bs-12261P
  • 2025年10月16日
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      500ug

    产品编号bs-12261P
    英文名称RTF1 Antibody Blocking Peptide
    中文名称组织相容性复合物RTF1封闭多肽
    英文别名CDG1N; GTL 7; GTL7; KIAA0252; Ortholog of mouse gene trap locus 7; RNA polymerase associated protein RTF1 homolog; RNA polymerase-associated protein RTF1 homolog; RTF 1; RTF1; Rtf1 Paf1/RNA polymerase II complex component homolog; RTF1_HUMAN; rtf1L; YGL244W;
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Methylation

    Epigenetics and Nuclear Signaling > Transcription > Elongation factors

    Microbiology > Organism > Eukaryotic Microorganism > Yeast > Saccharomyces spp

    Stem Cells > Endothelial Progenitors > Endothelial Markers

    亚基Component of the PAF1 complex, which consists of CDC73, PAF1, LEO1, CTR9, RTF1 and WDR61; the association of RTF1 appears to be less stable than that of other subunits. At least in HeLa cells a N-terminal shorter form of RTF1 is also found in the complex.
    亚细胞定位Nucleus, nucleoplasm (By similarity).
    相似性Contains 1 Plus3 domain.
    功能Plays a role in transcription-coupled histone modification. Plays a role in regulation of transcription. Required for maximal induction of heat-shock genes (By similarity). Binds single-stranded DNA.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus.

     

     

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