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- Bioss
- bs-43109P
- 2025年10月16日
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- 规格：
100ug/500ug/20ug
| 规格： | 100ug | 产品价格： | ￥2280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6880.0 |
| 规格： | 20ug | 产品价格： | ￥680.0 |
| 产品编号 | bs-43109P |
| 英文名称 | Recombinant human MISRII protein, C-hFc (HEK293) |
| 中文名称 | 重组人缪勒激素2型受体受体蛋白 |
| 英文别名 | AMH type II receptor; AMHR2; AMHR2_HUMAN; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; MGC141312; MIS type II receptor; MISRII; MRII; Muellerian hormone type 2 receptor; Muellerian hormone type II receptor; Mullerian hormone receptor type II;Recombinant human MISRII protein, C-hFc (HEK293) |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 40.2 |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | PBS (pH=7.4). |
| 研究领域 | Signal Transduction > Growth Factors/Hormones > TGF Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases Stem Cells > Signaling Pathways > TGF beta > Surface Molecules |
| 亚细胞定位 | Membrane. |
| 相似性 | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
TGFB receptor subfamily. Contains 1 protein kinase domain. |
| 功能 | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors phospho-rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant human MISRII protein, C-hFc (HEK293)(bs-43109P)-100ug/500ug/20ug
￥680 - 6880
