FOXRED1 Antibody Blocking Peptide(bs-13209P)-500ug

FOXRED1 Antibody Blocking Pept

ide(bs-13209P)-500ug
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  • ¥880
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  • bs-13209P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-13209P
    英文名称FOXRED1 Antibody Blocking Peptide
    中文名称单跨膜蛋白FOXRED1封闭多肽
    英文别名FAD dependent oxidoreductase domain containing 1; FAD dependent oxidoreductase domain containing protein 1; FAD-dependent oxidoreductase domain-containing protein 1; FOXRED 1; FOXRED1; FP634; FXRD1_HUMAN; H17.
    纯化方法HPLC
    研究领域

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Signal Transduction > Metabolism > Mitochondrial

    Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones

    亚细胞定位Membrane; Single-pass membrane protein (Potential).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome.

     

     

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