ABCD4 Antibody Blocking Peptide(bs-11908P)-500ug

ABCD4 Antibody Blocking Peptid

e(bs-11908P)-500ug
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  • bs-11908P
  • 2025年10月16日
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      500ug

    产品编号bs-11908P
    英文名称ABCD4 Antibody Blocking Peptide
    中文名称三磷酸腺苷结合盒转运蛋白4封闭多肽
    英文别名ABC 41; ABC41; ABCD 4; ABCD4; ABCD4_HUMAN; ATP binding cassette sub family D (ALD) member 4; ATP binding cassette sub family D member 4; ATP-binding cassette sub-family D member 4; P70R antibodyP79R; Peroxisomal membrane protein 1 like; Peroxisomal membrane protein 1-like; Peroxisomal membrane protein 69; PMP 69; PMP69; PMP70-related protein; XMP 1L; PXMP1 L; PXMP1-L; PXMP1L.
    纯化方法HPLC
    研究领域

    Tags & Cell Markers > Subcellular Markers > Organelles > Peroxisome

    亚基Homodimer or heterodimer
    亚细胞定位Peroxisome membrane; Multi-pass membrane protein.
    组织特异性Ubiquitous.
    相似性Belongs to the ABC transporter superfamily.
    ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 gene causes X-linked adreno-leukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises two quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD1 localizes to peroxisomes. ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol.

     

     

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