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- bs-14393P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14393P |
| 英文名称 | DNAJC5B Antibody Blocking Peptide |
| 中文名称 | DNAJC5B蛋白封闭多肽 |
| 英文别名 | Beta CSP; Beta cysteine string protein; CSP beta; DNJ5B_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 5 beta; DnaJ homolog subfamily C member 5B; MGC26226. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones |
| 亚细胞定位 | Membrane; Lipid-anchor. |
| 组织特异性 | Testis specific. |
| 翻译后修饰 | Palmitoylated. Palmitoylation is not required for membrane association. |
| 相似性 | Contains 1 J domain. |
| 功能 | DnaJ is a testis-specific heat shock protein and functions in association with DnaK(Hsp70). It is a molecular chaperone to facilitate protein folding. DnaJ plays a key role in the chaperone reaction by stimulating the ATPase activity and activating the substrate binding of Hsp70. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The DnaJ family, one of the largest of all the chaperone families, has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat-shock induced proteins are derived from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Members of this family contain cysteine-rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for the chaperone function. They are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC5B is a 199 amino acid protein that contains one J domain and plays an important role in exocytosis. DnaJC5B is expressed in testis where it is tightly bound to lipid membranes. The palmitoylation level of DnaJC5B is thought to correlate with its targeting to specific membranes. |
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DNAJC5B Antibody Blocking Peptide(bs-14393P)-500ug
￥880
