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Striatin 3/SG2NA Antibody Bloc

king Peptide(bs-12135P)-500ug
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  • ¥880
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  • bs-12135P
  • 2025年10月16日
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      500ug

    产品编号bs-12135P
    英文名称Striatin 3/SG2NA Antibody Blocking Peptide
    中文名称细胞周期蛋白SG2N封闭多肽
    英文别名Striatin3; Striatin-3; Striatin 3; Cell cycle autoantigen SG2NA; Cell cycle S/G2 nuclear autoantigen; GS2NA; nuclear autoantigen; S/G2 antigen; SG2NA; Striatin 3; Striatin, calmodulin binding protein 3; STRN3_HUMAN.
    纯化方法HPLC
    研究领域

    Immunology > Immune System Diseases > Autoimmune

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway

    亚基Interacts with protein phosphatase 2A (PP2A) (Potential).
    亚细胞定位Cytoplasm. Membrane; Peripheral membrane protein.
    相似性Belongs to the WD repeat striatin family.
    Contains 6 WD repeats.
    功能Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.

     

     

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