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500ug
| 产品编号 | bs-12135P |
| 英文名称 | Striatin 3/SG2NA Antibody Blocking Peptide |
| 中文名称 | 细胞周期蛋白SG2N封闭多肽 |
| 英文别名 | Striatin3; Striatin-3; Striatin 3; Cell cycle autoantigen SG2NA; Cell cycle S/G2 nuclear autoantigen; GS2NA; nuclear autoantigen; S/G2 antigen; SG2NA; Striatin 3; Striatin, calmodulin binding protein 3; STRN3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Immune System Diseases > Autoimmune Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway |
| 亚基 | Interacts with protein phosphatase 2A (PP2A) (Potential). |
| 亚细胞定位 | Cytoplasm. Membrane; Peripheral membrane protein. |
| 相似性 | Belongs to the WD repeat striatin family. Contains 6 WD repeats. |
| 功能 | Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
ELISA Procedure for Measuring Serum Antibody Titer
of an antibody is shown in Figure 22. The titer was estimated to be 1 in 2400. Figure 22. Antibody titer graph (X = dilution corresponding to Ab titer) Further Methods for Evaluating Anti-peptide Antibodies If the antibodies are to be used as a reagent
Synthesis and Probing of Membrane-bound Peptide Arrays
can be made. For the introduction of randomized X positions in the peptide sequences, take the appropriate Fmoc-AA-mix stock solution from the freezer, bring to room temperature, and activate by adding DIC (1.5 µl per 100 µl-vial
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