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500ug
| 产品编号 | bs-16110P |
| 英文名称 | INTS8 Antibody Blocking Peptide |
| 中文名称 | 8号染色体开放阅读框52封闭多肽 |
| 英文别名 | C8orf52; Chromosome 8 open reading frame 52; FLJ20530; INT8; Integrator complex subunit 8; INTS 8; INT8_HUMAN ; INTS8; KAONASHI protein 1; KAONASHI1; MGC131633. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing |
| 亚基 | Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. |
| 亚细胞定位 | Nuclear |
| 相似性 | Contains 4 TPR repeats. |
| 功能 | FLJ20530 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3' box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
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INTS8 Antibody Blocking Peptide(bs-16110P)-500ug
¥880







