TAZ Antibody Blocking Peptide(bs-15504P)-500ug

TAZ Antibody Blocking Peptide(

bs-15504P)-500ug
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  • bs-15504P
  • 2025年10月16日
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      500ug

    产品编号bs-15504P
    英文名称TAZ Antibody Blocking Peptide
    中文名称Tafazzin蛋白封闭多肽
    英文别名Barth syndrome; Cardiomyopathy dilated 3A (X linked); EFE2; Endocardial fibroelastosis 2; Protein G4.5; Tafazzin; TAZ; TAZ protein; TAZ protein; TAZ_HUMAN.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Stem Cells > Mesenchymal Stem Cells > Intracellular

    亚细胞定位Isoform 1, 3, 4, 5, 7: Membrane; Single-pass membrane protein.
    Isoform 2, 6, 8, 9: Cytoplasm (Probable).
    组织特异性High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.
    相似性Belongs to the taffazin family.
    功能Some isoforms may be involved in cardiolipin (CL) metabolism.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008].

     

     

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