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- Bioss
- bs-22012P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-22012P |
| 英文名称 | HEPACAM2 Antibody Blocking Peptide |
| 中文名称 | 肝细胞粘附分子2封闭多肽 |
| 英文别名 | RGD1305697; AI987662; HEPACAM 2; HEPACAM family member 2; LOC253012; HECA2_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, centrosome. Midbody. Note=In interphase, localizes to the Golgi apparatus. Localizes to centrosomes and spindles during prophase, prometaphase, and metaphase of mitosis, and to midbodies at telophase. Translocation to mitotic centrosomes is the result of poly-ADP-ribosylation (PARsylation). |
| 组织特异性 | Widely expressed. |
| 翻译后修饰 | Poly-ADP-ribosylated (PARsylated) by tankyrase TNKS during late G2 and prophase, leading to translocation to mitotic centrosomes. N-glycosylated. |
| 相似性 | Contains 2 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Widely expressed. |
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HEPACAM2 Antibody Blocking Peptide(bs-22012P)-500ug
￥880
