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500ug
| 产品编号 | bs-16057P |
| 英文名称 | FCF1 Antibody Blocking Peptide |
| 中文名称 | FCF1蛋白封闭多肽 |
| 英文别名 | Bka; C14orf111; CGI 35; Fcf1; FCF1 small subunit (SSU) processome component homolog (S. cerevisiae); FCF1_HUMAN; rRNA processing protein FCF1 homolog; rRNA-processing protein FCF1 homolog. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus > nucleolus. |
| 相似性 | Belongs to the UTP23/FCF1 family. FCF1 subfamily. Contains 1 PINc domain. |
| 功能 | Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Ribosomes are the organelles that catalyze protein synthesis. Ribosomes consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. FCF1 is a 198 amino acid protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. The gene encoding FCF1 maps to human chromosome 14, which contains about 700 genes and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder α1-antitrypsin deficiency. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. |
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FCF1 Antibody Blocking Peptide(bs-16057P)-500ug
¥880







