NAT2 Antibody Blocking Peptide(bs-2798P)-500ug

NAT2 Antibody Blocking Peptide

(bs-2798P)-500ug
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  • ¥880
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  • bs-2798P
  • 2025年10月16日
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      500ug

    产品编号bs-2798P
    英文名称NAT2 Antibody Blocking Peptide
    中文名称N-乙酰基转移酶2封闭多肽
    英文别名AAC2; Arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation); Arylamide acetylase 2; Arylamine N-acetyltransferase 2; HGNC:7646; N-acetyltransferase 2 (arylamine N-acetyltransferase); ARY2_HUMAN.
    纯化方法HPLC
    研究领域

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism

    Signal Transduction > Metabolism > Drug metabolism

    亚细胞定位Cytoplasm.
    相似性Belongs to the arylamine N-acetyltransferase family.
    功能Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq].

     

     

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