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- Bioss
- bs-1187P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1187P |
| 英文名称 | PAX2 Antibody Blocking Peptide |
| 中文名称 | 配对盒基因2封闭多肽 |
| 英文别名 | PAX2 Paired box gene 2; Paired box gene 2; paired box homeotic gene 2; paired box protein 2; Paired box protein Pax 2; Paired box protein Pax-2; Paired box protein Pax2; Pax 2. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Organogenesis > Excretory system development > Kidney development Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > PAX Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Neuroscience > Cell Type Marker > Neural Stem Cell marker |
| 亚基 | Interacts with ELGN3; the interaction targets PAX2 for destruction. |
| 亚细胞定位 | Nuclear. |
| 组织特异性 | Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system. |
| 相似性 | Contains 1 paired domain. |
| 功能 | Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
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PAX2 Antibody Blocking Peptide(bs-1187P)-500ug
￥880
