RGS5 Antibody Blocking Peptide(bs-2794P)-500ug

RGS5 Antibody Blocking Peptide

(bs-2794P)-500ug
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  • ¥880
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  • bs-2794P
  • 2025年10月16日
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      500ug

    产品编号bs-2794P
    英文名称RGS5 Antibody Blocking Peptide
    中文名称G蛋白信号转导调节因子5封闭多肽
    英文别名MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129; Regulator of G Protein Signalling 5; RGS 5; RGS5_HUMAN.
    纯化方法HPLC
    研究领域

    Cardiovascular > Angiogenesis > Angiogenic Factors

    Cardiovascular > Blood > Blood Pressure regulation

    Cardiovascular > Heart > Hypertrophy

    Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators

    亚细胞定位Isoform 1: Cytoplasm,Membrane. Isoform 2: Cytoplasm.
    相似性Contains 1 RGS domain.
    功能Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi and Gq class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination. RGS5 seems to be an important signalling regulator in the vascular system. Present data suggest that RGS5 may be involved in the regulation of capillary growth, angiogenesis, and in the pathophysiology of stroke.

     

     

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