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- Bioss
- bs-11870P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-11870P |
| 英文名称 | LHX5 Antibody Blocking Peptide |
| 中文名称 | LHX5蛋白封闭多肽 |
| 英文别名 | LHX 5; Lhx5; LHX5_HUMAN; LIM homeobox 5; LIM homeobox protein 5; LIM/homeobox protein Lhx5; MGC129689. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > LIM Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in fetal brain and in various regions of the adult central nervous system including the spinal cord, the thalamus, and the cerebellum. |
| 相似性 | Contains 1 homeobox DNA-binding domain. Contains 2 LIM zinc-binding domains. |
| 功能 | Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The human LHX5 gene maps to chromosome 12q23-q24 and encodes a 402 amino acid protein. The hippocampus contains the neural circuitry, which is crucial for cognitive functions such as learning and memory. LHX5 regulates precursor cell proliferation and neuronal differentiation and migration during hippocampal development. |
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LHX5 Antibody Blocking Peptide(bs-11870P)-500ug
￥880
