FKBP11 Antibody Blocking Peptide(bs-13176P)-500ug

FKBP11 Antibody Blocking Pepti

de(bs-13176P)-500ug
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  • ¥880
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  • bs-13176P
  • 2025年10月16日
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      500ug

    产品编号bs-13176P
    英文名称FKBP11 Antibody Blocking Peptide
    中文名称肽基脯氨酰顺反异构酶FKBP11封闭多肽
    英文别名19 kDa FK506 binding protein; 19 kDa FK506-binding protein; 19 kDa FKBP; FK506 binding protein 11 (19 kDa); FK506 binding protein 11; FK506-binding protein 11; FKB11_HUMAN; FKBP 19; FKBP-11; FKBP-19; Fkbp11; FKBP19; MGC54182; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP11; PPIase; PPIase FKBP11; Rotamase.
    纯化方法HPLC
    亚细胞定位Membrane; Single-pass membrane protein (Potential).
    相似性Belongs to the FKBP-type PPIase family.
    Contains 1 PPIase FKBP-type domain.
    功能PPIases accelerate the folding of proteins during protein synthesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Immunophilins have also been implicated in protein folding and trafficking within the endoplasmic reticulum (ER). FKBP11 (FK506-binding protein 11), also known as FKBP19 or peptidyl-prolyl cis-trans isomerase FKBP11, is a 201 amino acid single-pass membrane protein belonging to the FKBP-type PPIase family, a group of proteins known to catalyze the folding of proline-containing polypeptides. Containing one PPIase FKBP-type domain, FKBP11 is expressed in secretory tissues such as pancreas, pituitary, stomach, lymph node and salivary gland, and is encoded by a gene that maps to human chromosome 12q13.12. FK506 and rapamycin are known to inhibit FKBP11’s peptidyl-prolyl isomerase activity.

     

     

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