DMRTC1 Antibody Blocking Peptide(bs-14350P)-500ug

DMRTC1 Antibody Blocking Pepti

de(bs-14350P)-500ug
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  • ¥880
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  • bs-14350P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-14350P
    英文名称DMRTC1 Antibody Blocking Peptide
    中文名称DMRTC1蛋白封闭多肽
    英文别名DMRT like family C1; Dmrtc1; DMRTC_HUMAN; DMRTC1B; Doublesex and mab 3 related transcription factor C1; Doublesex mab 3.
    纯化方法HPLC
    亚细胞定位Nuclear
    组织特异性Predominantly expressed in kidney, pancreas, ovary and testis. Detected in brain and in many other tissues.
    相似性Belongs to the DMRT family.
    功能The vertebrate DMRT gene family encodes putative transcription factors related to the sexual regulators Doublesex (Drosophila) and MAB-3 (Worm).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料DMRTC1 is a 182 amino acid nuclear protein that exists as three alternatively spliced isoforms and belongs to the DMRT family. Involved in sexual development, DMRTC1 is expressed in Sertoli cells in male testis but, unlike other DMRT family members, it does not contain a DM DNA-binding domain. The gene encoding DMRTC1 maps to the human X chromosome, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited, including Klinefelter's syndrome, Turner's syndrome, and Triple X syndrome.

     

     

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