Kir7.1 Antibody Blocking Peptide(bs-17074P)-500ug

Kir7.1 Antibody Blocking Pepti

de(bs-17074P)-500ug
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  • bs-17074P
  • 2025年10月16日
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      500ug

    产品编号bs-17074P
    英文名称Kir7.1 Antibody Blocking Peptide
    中文名称钾离子通道蛋白Kir7.1封闭多肽
    英文别名Inward rectifier K(+) channel Kir7.1; Inward rectifier potassium channel 13; inwardly rectifying subfamily J member 13; IRK13_HUMAN; KCNJ13; KIR1.4; KIR7.1; LCA16; Potassium channel; Potassium inwardly rectifying channel subfamily J member 13; SVD.
    纯化方法HPLC
    亚细胞定位Membrane.
    组织特异性Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord.
    相似性Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ13 subfamily.
    功能Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the inwardly rectifying potassium channel family of proteins. Members of this family form ion channel pores that allow potassium ions to pass into a cell. The encoded protein belongs to a subfamily of low signal channel conductance proteins that have a low dependence on potassium concentration. Mutations in this gene are associated with snowflake vitreoretinal degeneration. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

     

     

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