PILRB Antibody Blocking Peptide(bs-2690P)-500ug

PILRB Antibody Blocking Peptid

e(bs-2690P)-500ug
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  • ¥880
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  • bs-2690P
  • 2025年10月16日
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      500ug

    产品编号bs-2690P
    英文名称PILRB Antibody Blocking Peptide
    中文名称细胞表面受体PILRβ封闭多肽
    英文别名PILRB; Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR beta; Cell surface receptor FDFACT; Cell surface receptor FDFACT1; Cell surface receptor FDFACT2; FDFACT; FDFACT1; FDFACT2; Paired immunoglobulin like receptor beta; Paired immunoglobulin like type 2 receptor beta; Paired immunoglobulin like type 2 receptor beta precursor;
    纯化方法HPLC
    研究领域

    Immunology > Adaptive Immunity > T Cells > CD

    Immunology > Innate Immunity > NK Cells

    Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases

    亚细胞定位Membrane; Single-pass type I membrane protein (Potential).
    相似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    功能Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.

     

     

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