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GLI4 Antibody Blocking Peptide

(bs-13373P)-500ug
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  • ¥880
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  • bs-13373P
  • 2025年10月16日
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      500ug

    产品编号bs-13373P
    英文名称GLI4 Antibody Blocking Peptide
    中文名称转录因子Gli4/锌指蛋白gli4封闭多肽
    英文别名GLI 4; GLI Kruppel family member GLI 4; GLI Kruppel family member GLI4; GLI4; GLI4_HUMAN; HKR 4; HKR4; HKR4 protein; Krueppel related zinc finger protein 4; Krueppel-related zinc finger protein 4; Neural specific DNA binding protein; Oncogene HKR 4; Oncogene HKR4; Protein HKR 4; Protein HKR4; Zinc finger protein GLI 4; Zinc finger protein GLI4.
    纯化方法HPLC
    亚细胞定位Nucleus.
    相似性Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 7 C2H2-type zinc fingers.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. GLI-4, also known as HKR4, is a 376 amino acid protein that localizes to the nucleus and contains seven C2H2-type zinc fingers. Belonging to the krueppel C2H2-type zinc-finger protein family, GLI-4 may function as a transcriptional regulator, effectively activating or repressing the transcription of target genes. The gene encoding GLI-4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

     

     

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