DCDC2 Antibody Blocking Peptide(bs-11824P)-500ug

DCDC2 Antibody Blocking Peptid

e(bs-11824P)-500ug
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  • bs-11824P
  • 2025年10月16日
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      500ug

    产品编号bs-11824P
    英文名称DCDC2 Antibody Blocking Peptide
    中文名称双皮层蛋白结构域蛋白DCDC2封闭多肽
    英文别名DCDC 2; DCDC2; DCDC2_HUMAN; DCDC2A; Doublecortin domain containing 2; Doublecortin domain-containing protein 2; HGNC:18141; KIAA1154; Protein RU2S; RU2; RU2S; RU2S protein.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurology process > Neurogenesis

    Neuroscience > Sensory System > Visual system

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > Tubulin

    组织特异性Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus.
    相似性Contains 2 doublecortin domains.
    功能May be involved in neuronal migration during development of the cerebral neocortex.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The DCDC2 gene encodes the DCDC2 protein (Doublecortin-containing protein 2, RU2, RU2S) which contains two Doublecortin peptide domains similar to those in the Doublecortin gene. DCDC2 is transcribed as a “normal” gene, which results in a sense transcript (RU2S), but when it is transcribed in the opposite direction, a shorter antisense transcript (RU2AS), which is found in tumors, results. The DCDC2 protein demonstrates ubiquitous expression, whereas RU2AS expression is restricted to normal kidney, bladder, liver and testis, and to tumors of various histologic origins. The deduced DCDC2 protein contains 476 amino acids, while the RU2AS protein contains 84 residues. There is a significant association between dyslexia and several SNPs within the DCDC2 gene.

     

     

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