- ￥880
- Bioss
- bs-11813P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11813P |
| 英文名称 | BTD/Biotinidase Antibody Blocking Peptide |
| 中文名称 | 生物素酶封闭多肽 |
| 英文别名 | Biotinase; Biotinidase; Btd; Sp8; BTD_HUMAN; EC 3.5.1.12. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Neuroscience > Neurology process > Neurogenesis Signal Transduction > Metabolism > Energy Metabolism |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the CN hydrolase family. BTD/VNN subfamily. Contains 1 CN hydrolase domain. |
| 功能 | Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Biotin, also known as vitamin B7, is an essential water-soluble vitamin that is a cofactor in glucogenesis and in the metabolism of fatty acids and leucine. Biotinidase is a 523 amino acid enzyme that catalyzes the hydrolysis of biocytin to biotin and lysine. Secreted into extracellular space, biotinidase is expressed in liver, heart, placenta, brain, skeletal muscle, pancreas and kidney. Biotinidase contains one carbon-nitrogen hydrolase domain, which is involved in the reduction of organic nitrogen compounds and ammonia production. Defects in the gene encoding biotinidase are the cause of biotinidase deficiency, which is characterized by skin rash, ataxia, seizures, hearing loss, hypotonia and optic atrophy. These symptoms are due to the individual’s inability to reutilize biotin and can, therefore, typically be treated with the addition of free biotin. |
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BTD/Biotinidase Antibody Blocking Peptide(bs-11813P)-500ug
￥880
