- ￥880
- Bioss
- bs-12452P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12452P |
| 英文名称 | AIPL1 Antibody Blocking Peptide |
| 中文名称 | 遗传性失明相关蛋白AIPL1封闭多肽 |
| 英文别名 | A930007I01Rik; Aipl1; AIPL1_HUMAN; AIPL2; Aryl hydrocarbon interacting protein like 1; Aryl hydrocarbon receptor interacting protein like 1; Aryl-hydrocarbon-interacting protein-like 1; LCA4; MGC25485; OTTHUMP00000128207; OTTMUSP00000006382; RP23-401C17.1. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Visual system Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones |
| 亚基 | Interacts with NUB1. |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Highly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina. |
| 相似性 | Contains 1 PPIase FKBP-type domain. Contains 3 TPR repeats. |
| 功能 | May be important in protein trafficking and/or protein folding and stabilization. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The inherited blindness associated protein, aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), interacts with the cell cycle regulator protein NUB1. AIPL1 is crucial for protein folding and stabilization, as well as for protein trafficking. It localizes to the nucleus or cytoplasm and is highly expressed in the pineal gland and the retina. In the retina, AIPL1 is expressed in both developing cone and rod photoreceptors, but it is restricted to rod photoreceptors in the adult human retina. Defects in the gene encoding for AIPL1 can cause Leber congenital amaurosis type IV, an early-onset, inherited autosomal recessive disorder that results in childhood blindness. |
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AIPL1 Antibody Blocking Peptide(bs-12452P)-500ug
￥880
