LRRC1 Antibody Blocking Peptide(bs-17099P)-500ug

LRRC1 Antibody Blocking Peptid

e(bs-17099P)-500ug
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  • ¥880
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  • bs-17099P
  • 2025年10月16日
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      500ug

    产品编号bs-17099P
    英文名称LRRC1 Antibody Blocking Peptide
    中文名称富含亮氨酸重复序列蛋白1封闭多肽
    英文别名dJ523E19.1; FLJ10775; FLJ11834; LANO adapter protein; LAP and no PDZ protein; Leucine rich repeat containing protein 1; Leucine-rich repeat-containing protein 1; Lrrc1; LRRC1_HUMAN.
    纯化方法HPLC
    亚基Interacts with DLG1 and DLG4. May form a complex with DLG1 and ERBB2IP, where interaction between LRRC1 and ERBB2IP is indirect.
    亚细胞定位Cytoplasm. Membrane. Localized at the basolateral side of epithelial cells.
    组织特异性Expressed strongly in testis and placenta, followed by heart, lung, kidney, thyroid, trachea, colon, prostate and pancreas.
    相似性Contains 17 LRR (leucine-rich) repeats.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. LRRC1 (leucine-rich repeat-containing protein 1), also known as LANO adapter protein or LAP and no PDZ protein, is a 524 amino acid protein that contains 17 LRR repeats. Localized to the cytoplasm and the membrane, LRRC1 is expressed strongly in placenta and testis, with lower levels found in heart, kidney, thyroid, lung, prostate, colon and trachea. LRRC1 interacts with PSD-95 and SAP 97, and may form a complex with SAP 97 and ERBIN. LRRC1 is expressed as two isoforms produced by alternative splicing events.

     

     

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