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500ug
| 产品编号 | bs-13861P |
| 英文名称 | CEP72 Antibody Blocking Peptide |
| 中文名称 | 中心体蛋白72封闭多肽 |
| 英文别名 | Centrosomal protein 72kDa; Centrosomal protein of 72 kDa; Cep72; CEP72_HUMAN; FLJ10565; MGC5307; RGD1566336. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cytoplasm; cytoskeleton; centrosome. Localizes to the centrosome and centrosome-surrounding particles throughout the cell cycle. These particles disappear after microtubules are depolymerized using nocodazole, suggesting that CEP72-associating particles localize in a microtubule-dependent manner. |
| 相似性 | Belongs to the CEP72 family. Contains 3 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. |
| 功能 | Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ/PLK1S1, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The product of this gene is a member of the leucine-rich-repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. [provided by RefSeq, Jul 2008] |
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CEP72 Antibody Blocking Peptide(bs-13861P)-500ug
¥880








