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- Bioss
- bs-17076P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-17076P |
| 英文名称 | KAT2A Antibody Blocking Peptide |
| 中文名称 | 组蛋白乙酰基转移酶GCN5封闭多肽 |
| 英文别名 | 1110051E14Rik; AW212720; EC 2.3.1.48; GCN 5; GCN5 (general control of amino acid synthesis yeast homolog) like 2; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; Gcn5; GCN5 general control of amino acid synthesis 5 like 2; GCN5 general control of amino-acid synthesis 5-like 2 (yeast); GCN5 like 2; GCN5L2; general control of amino acid synthesis 5-like 2; General control of amino acid synthesis protein 5 like 2; General control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis yeast homolog like 2; General control of amino acid synthesis, yeast, homolog-like 2; HGCN 5; HGCN5; Histone acetyltransferase GCN5; Histone acetyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2 A; KAT2A; KAT2A_HUMAN; Lysine acetyltransferase 2A; MGC102791; PCAF-b; STAF97. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Bromodomains Epigenetics and Nuclear Signaling > ChIP assays > ChIP antibodies Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Acetylation Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Acetylation > HAT Epigenetics and Nuclear Signaling > Transcription > Co-factors |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in all tissues tested, with most abundant expression in ovary. |
| 相似性 | Belongs to the GCN5 family. Contains 1 bromo domain. Contains 1 N-acetyltransferase domain. |
| 功能 | Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009] |
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KAT2A Antibody Blocking Peptide(bs-17076P)-500ug
￥880
