BSP Antibody Blocking Peptide(bs-2668P)-500ug

BSP Antibody Blocking Peptide(

bs-2668P)-500ug
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  • bs-2668P
  • 2025年10月16日
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      500ug

    产品编号bs-2668P
    英文名称BSP Antibody Blocking Peptide
    中文名称骨涎蛋白封闭多肽
    英文别名BNSP; Bone sialoprotein II; BSP; BSPII; Cell binding sialoprotein; Integrin binding sialoprotein; SPII; SIAL_HUMAN; Bone sialoprotein 2; BSP II; Cell-binding sialoprotein; Integrin-binding sialoprotein.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    Stem Cells > Mesenchymal Stem Cells > Osteogenesis

    亚细胞定位Secreted.
    翻译后修饰N-glycosylated; glycans consist of sialylated and core-fucosylated bi-, tri- and tetraantennary chains.
    Sulfated on either Tyr-320 or Tyr-321 (By similarity).
    功能Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]

     

     

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