- ￥880
- Bioss
- bs-11907P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11907P |
| 英文名称 | ABCB9 Antibody Blocking Peptide |
| 中文名称 | 腺苷三磷酸结合盒转运体9封闭多肽 |
| 英文别名 | ABC transporter 9 protein; ABCB 9; ATP binding cassette sub family B (MDR/TAP) member 9; ATP binding cassette sub family B member 9 precursor; ATP binding cassette transporter 9; EST122234; ABCB9; KIAA1520; TAP like protein; TAPL; ABCB9_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Drug metabolism |
| 亚基 | Homodimer. |
| 亚细胞定位 | Integral membrane protein. Lysosomal. May be localized in the endoplasmic reticulum. |
| 组织特异性 | Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages. |
| 相似性 | Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain. |
| 功能 | The membrane associated protein encoded by this gene is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in three known products which are likely to have different substrate specifications. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. As the largest family of transmembrane proteins, ABC genes comprise several subfamilies (ABC1, ABCA, ABCE, ABCF, MDR/TAP, MRP, ALD, OABP, GCN20 and White (also known as ABCG)). In bacteria, ABC transporters are used to import compunds that cannot be obtained by diffusion. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process or outside the cell for transport to other organs, or for secretion from the body. ABCB9 (also designated Transporter associated with antigen processing (TAP)-like or TAPL) forms a homodimer, which is localized in lysosomes. It functions as an ATP-dependent peptide transporter that shows a broad peptide specificity ranging from 6-mer up to 59-mer peptides. ABCB9 transports these peptides with low affinity but high efficiency. |
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ABCB9 Antibody Blocking Peptide(bs-11907P)-500ug
￥880
